Cushing's Syndrome

Cushing's syndrome is a hormonal disorder caused by prolonged exposure to high levels of cortisol. Cortisol, a hormone produced by the adrenal glands, helps regulate metabolism, blood pressure, and stress responses. When the body produces too much cortisol or receives it from external sources, it can lead to various health complications.

Causes of Cushing’s Syndrome

Cushing’s syndrome can result from:

• Prolonged corticosteroid use: Long-term use of steroid medications for conditions like asthma or autoimmune diseases.
• Cushing’s disease: A tumor in the pituitary gland that overproduces adrenocorticotropic hormone (ACTH), stimulating excessive cortisol release.
• Adrenal gland tumors: Growths in the adrenal glands that independently produce high cortisol levels.
• Ectopic ACTH syndrome: Some lung or pancreatic tumors can produce ACTH, leading to excess cortisol.

Common Symptoms of Cushing’s Syndrome

Excess cortisol can cause noticeable physical and metabolic changes, such as:

• Unexplained weight gain, especially around the abdomen and face (moon face)
• Fatty deposits between the shoulders (buffalo hump)
• Skin thinning, bruising easily, and slow wound healing
• Muscle weakness and fatigue
• High blood pressure and blood glucose levels
• Mood changes, anxiety, or depression
• Osteoporosis and increased fracture risk
• Irregular menstrual cycles in women

How Cushing’s Syndrome Affects the Body

Cortisol plays a vital role in many body functions, and its excess can have serious effects:

• Metabolic disturbances: Leads to insulin resistance and weight gain.
• Cardiovascular impact: Increases the risk of hypertension and heart disease.
• Bone health deterioration: Weakens bones, making them prone to fractures.

Diagnostic Approach

At Precision Care: Endocrinology & Diabetes, we use advanced testing to diagnose Cushing’s syndrome:

• 24-hour urinary free cortisol test to measure cortisol levels in urine.
• Dexamethasone suppression test to evaluate how the body regulates cortisol.
• Salivary cortisol test to detect abnormal hormone patterns.
• Imaging scans (MRI/CT) to identify tumors in the pituitary or adrenal glands.

Why Choose Us?

At Precision Care: Endocrinology & Diabetes, we provide:

• Specialised expertise in endocrine disorders
• Comprehensive diagnostic services for accurate assessment
• Personalised care plans for managing hormonal imbalances
• A patient-centred approach to long-term wellbeing

Consult us today for expert evaluation and care. Early diagnosis and management are key to preventing complications and improving overall health.